Infectious-inflammatory diseases caused by susceptible organisms: respiratory tract infections (bronchitis, pneumonia), upper respiratory tract (sinusitis, pharyngitis, otitis media, laryngitis), skin, soft tissues, bones, joints, infectious and inflammatory testosterone propionate side effects diseases of the abdominal cavity and biliary tract, the kidneys (pyelonephritis), urinary tract (cystitis, urethritis), pelvic organs (endometritis, salpingitis, oophoritis, cervicitis, Options, prostatitis), genitals (coleitis, orchitis, epididymitis), gonorrhea, chlamydia; meningitis; prevention of infections in patients with impaired immune status (including neutropenia).
Hypersensitivity to the components of the preparation, lack of glucose-6-phosphate dehydrogenase, epilepsy (including history), lowering the seizure threshold (including after craniocerebral trauma, stroke or inflammation in the central nervous system); age up to 18 years (not yet completed skeletal growth), pregnancy, lactation, tendons defeat at the earlier treatment of quinolones.
Be wary – cerebral atherosclerosis, cerebrovascular accidents (in history), chronic renal failure, organic lesions of the central nervous system, lengthening the interval QT.
DOSAGE AND ADMINISTRATION
dose of ofloxacin and the duration of treatment depend on the severity and type of infection, the patient’s general condition and renal function.
The average daily dose for adults – from 200 mg to 600 mg. Treatment duration -7-10 days.
The dose to 400 mg testosterone propionate side effects per day may be administered in one administration, preferably in the morning. Doses of 400 mg per day should be divided into 2 doses with regular intervals. Tablets should be taken whole with a glass of water both before and during the meal. It is necessary to avoid the simultaneous reception with antacids.
In severe infections, or in patients who are overweight daily dose may be increased to 800 mg.
In uncomplicated infections of lower urinary tract the drug is prescribed in a dose of 200 mg per day for 3-5 days. In gonorrhea appoint 400 mg once daily.
In patients with impaired renal function (when creatinine clearance 50-20 ml / min), the single dose should be 50% of the average doses for the multiplicity of 2 times a day, or a full single dose is administered 1 time per day .
When a creatinine clearance less than 20 mL / min, initial dose – 200 mg, and then – 100 mg a day every other day.
in hemodialysis and peritoneal dialysis -. 100 mg every 24 hours
in patients with liver failure, do not exceed the maximum daily dose 400 mg.
Initiated intravenous treatment may be continued ofloxacin tablet form of the drug at the same dose (for improving patient).
ADVERSE EFFECTS From the digestive system: gastralgia, anorexia, nausea, vomiting, diarrhea, flatulence, abdominal pain, increased activity of “liver” transaminases, hyperbilirubinemia, cholestatic jaundice, pseudomembranous enterocolitis, hepatitis. Nervous system: headache, dizziness, uncertainty movements, tremors, convulsions, numbness and paresthesias of extremities, intense dreams, “nightmarish” dream, psychotic reactions, anxiety, state of arousal, phobias, depression, confusion, hallucinations, increased intracranial pressure. From the musculoskeletal system: tendonitis, myalgias , arthralgia, tenosynovitis, tendon rupture, rhabdomyolysis, muscle weakness. From the senses: violation of color vision, diplopia, disturbances of taste, smell, hearing and balance. With the cardiovascular system: tachycardia, decreased blood pressure, vasculitis, collapse. Allergic reactions: skin rash, pruritus, urticaria, testosterone propionate side effects hypersensitivity pneumonitis, allergic nephritis, eosinophilia, fever, angioedema, bronchoconstriction, Stevens-Johnson syndrome and toxic epidermal necrolysis, erythema multiforme exudative, anaphylactic shock. For the skin: petechial hemorrhages (petechiae), dermatitis bullous hemorrhagic, papular rash with crusted showing vascular involvement (vasculitis). from the side of hematopoiesis: leukopenia, agranulocytosis, anemia, thrombocytopenia, pancytopenia, hemolytic and aplastic anemia. from the urinary system: acute interstitial nephritis, renal dysfunction, hypercreatininemia , elevated levels of urea. Other: goiter, superinfection, hypoglycemia (in patients with diabetes), photosensitivity, vaginitis.
Overdose symptoms: dizziness, confusion, lethargy, disorientation, drowsiness, and vomiting. Treatment: gastric lavage, symptomatic therapy. With hemodialysis removes 10 – 30% of the formulation. testosterone anabolic steroids zac efron steroids what are the effects of anabolic steroids